Nervous system

Headaches & Migraines in menopause

Hormonal fluctuations are one of the biggest migraine triggers in women.

41%
fewer headaches with magnesium
3×
more frequent in perimenopause
Headaches and migraines

Why do they happen?

Oestrogen influences serotonin synthesis and pain sensitivity. Its sharp fluctuations during perimenopause activate the trigeminal pain pathways — the central mechanism of migraine. In postmenopause, as levels stabilise, many women experience improvement.

Most common types

  • Hormonal migraine — linked to sudden oestrogen drops
  • Tension headache — related to stress and cervical muscle tension
  • Hot flash headache — after intense vasodilation episodes
Clinical evidence

Magnesium (400 mg/day) reduces hormonal migraine frequency by 41% in perimenopausal women. Most effective in bisglycinate or glycinate form taken before bed.

Preventive strategies

  • Magnesium bisglycinate 300–400 mg/day before bed
  • Regular sleep schedules — sleep deprivation is the main trigger
  • Headache diary to identify personal triggers
  • Constant hydration (at least 2 litres/day)
  • Gradually reduce caffeine — excess reinforces pain
Vive Tu Balance Selection

Life Extension Europe® Magnesium Glycinate

Magnesium bisglycinate (chelate) with high bioavailability and good digestive tolerance — the best-studied form for hormonal migraine. It provides 105 mg of elemental magnesium per capsule; adjust the number of capsules with your doctor or pharmacist to reach the recommended dose (300–400 mg/day).

Notice: this is not medical advice, but a suggestion for an over-the-counter product. Even though it is available without a prescription, consult your doctor before using it.

The information on this page is for general information only and does not replace advice from a healthcare professional. If a symptom worries you or affects your daily life, talk to your doctor or gynaecologist.

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